No association between the presence of periodontal disease and poor IVF outcomes: a pilot study
No association between the presence of periodontal disease and poor IVF outcomes: a pilot study
Blog Article
Dalia Khalife,1 Ali Khalil,1 Mohamad N Itani,2 Fatin Khalifeh,1 Sara Faour,1 Anastasia Salame,1 Ghina Ghazeeri11Department of Obstetrics & Gynecology, American University of Beirut Medical Center, Beirut, Lebanon; 2Department of Dentistry, American University of Beirut Medical Center, Beirut, LebanonBackground: Periodontal disease can lead to bacteremia with release of cytokines, affecting implantation in women trying to conceive through in vitro fertilization (IVF).A potential association Control Panel w/Keypad between maternal periodontal disease and poor IVF outcomes has been described.Objective: The aim of the study is to assess whether pre-existing periodontal disease has any effect on IVF parameters.
Method: A pilot study composed of 34 women was conducted at a tertiary care center.Prior to IVF, dental examination, IVF parameters were collected.Results: Thirty-four women participated in the study.
The outcomes of 28 women (82.3%) were analyzed.Out of the 28 patients, 17 patients had a positive pregnancy test (60.
7%) with a total of 13 live births (46.4%) and 4 pregnancy losses (14.3%).
Plaque and bleeding index scores were both lower in patients who achieved pregnancy after IVF yet did not reach statistical significance -2146826246 (p=0.309 and 0.422).
Comparison of mean values for the different infertility parameters showed no significant differences among women with different IVF outcomes (p>0.05).Different degrees of inflammation of the gingiva did not have an effect on the different clinical parameters and the live birth rates.
Conclusion: The evidence provided by the present study does not support the hypothesis.Addressing the status of oral health before any infertility treatment remains to be elucidated.Keywords: periodontal disease, in vitro fertilization, infertility, inflammation, live birth.